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Dissociation of Fatty Liver and Insulin Resistance in I148M PNPLA3 Carriers: Differences in Diacylglycerol (DAG) FA18:1 Lipid Species as a Possible Explanation
Fatty liver is tightly associated with insulin resistance and the development of type 2 diabetes. I148M variant in patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene is associated with high liver fat but normal insulin sensitivity. The underlying mechanism of the disassociation bet...
Autores principales: | Franko, Andras, Merkel, Dietrich, Kovarova, Marketa, Hoene, Miriam, Jaghutriz, Benjamin A., Heni, Martin, Königsrainer, Alfred, Papan, Cyrus, Lehr, Stefan, Häring, Hans-Ulrich, Peter, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164484/ https://www.ncbi.nlm.nih.gov/pubmed/30227635 http://dx.doi.org/10.3390/nu10091314 |
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