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Pre-imaginal conditioning alters adult sex pheromone response in Drosophila

Pheromones are chemical signals that induce innate responses in individuals of the same species that may vary with physiological and developmental state. In Drosophila melanogaster, the most intensively studied pheromone is 11-cis-vaccenyl acetate (cVA), which is synthezised in the male ejaculatory...

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Autores principales: Everaerts, Claude, Cazalé-Debat, Laurie, Louis, Alexis, Pereira, Emilie, Farine, Jean-Pierre, Cobb, Matthew, Ferveur, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164551/
https://www.ncbi.nlm.nih.gov/pubmed/30280017
http://dx.doi.org/10.7717/peerj.5585
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author Everaerts, Claude
Cazalé-Debat, Laurie
Louis, Alexis
Pereira, Emilie
Farine, Jean-Pierre
Cobb, Matthew
Ferveur, Jean-François
author_facet Everaerts, Claude
Cazalé-Debat, Laurie
Louis, Alexis
Pereira, Emilie
Farine, Jean-Pierre
Cobb, Matthew
Ferveur, Jean-François
author_sort Everaerts, Claude
collection PubMed
description Pheromones are chemical signals that induce innate responses in individuals of the same species that may vary with physiological and developmental state. In Drosophila melanogaster, the most intensively studied pheromone is 11-cis-vaccenyl acetate (cVA), which is synthezised in the male ejaculatory bulb and is transferred to the female during copulation. Among other effects, cVA inhibits male courtship of mated females. We found that male courtship inhibition depends on the amount of cVA and this effect is reduced in male flies derived from eggs covered with low to zero levels of cVA. This effect is not observed if the eggs are washed, or if the eggs are laid several days after copulation. This suggests that courtship suppression involves a form of pre-imaginal conditioning, which we show occurs during the early larval stage. The conditioning effect could not be rescued by synthetic cVA, indicating that it largely depends on conditioning by cVA and other maternally-transmitted factor(s). These experiments suggest that one of the primary behavioral effects of cVA is more plastic and less stereotypical than had hitherto been realised.
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spelling pubmed-61645512018-10-02 Pre-imaginal conditioning alters adult sex pheromone response in Drosophila Everaerts, Claude Cazalé-Debat, Laurie Louis, Alexis Pereira, Emilie Farine, Jean-Pierre Cobb, Matthew Ferveur, Jean-François PeerJ Animal Behavior Pheromones are chemical signals that induce innate responses in individuals of the same species that may vary with physiological and developmental state. In Drosophila melanogaster, the most intensively studied pheromone is 11-cis-vaccenyl acetate (cVA), which is synthezised in the male ejaculatory bulb and is transferred to the female during copulation. Among other effects, cVA inhibits male courtship of mated females. We found that male courtship inhibition depends on the amount of cVA and this effect is reduced in male flies derived from eggs covered with low to zero levels of cVA. This effect is not observed if the eggs are washed, or if the eggs are laid several days after copulation. This suggests that courtship suppression involves a form of pre-imaginal conditioning, which we show occurs during the early larval stage. The conditioning effect could not be rescued by synthetic cVA, indicating that it largely depends on conditioning by cVA and other maternally-transmitted factor(s). These experiments suggest that one of the primary behavioral effects of cVA is more plastic and less stereotypical than had hitherto been realised. PeerJ Inc. 2018-09-27 /pmc/articles/PMC6164551/ /pubmed/30280017 http://dx.doi.org/10.7717/peerj.5585 Text en ©2018 Everaerts et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Animal Behavior
Everaerts, Claude
Cazalé-Debat, Laurie
Louis, Alexis
Pereira, Emilie
Farine, Jean-Pierre
Cobb, Matthew
Ferveur, Jean-François
Pre-imaginal conditioning alters adult sex pheromone response in Drosophila
title Pre-imaginal conditioning alters adult sex pheromone response in Drosophila
title_full Pre-imaginal conditioning alters adult sex pheromone response in Drosophila
title_fullStr Pre-imaginal conditioning alters adult sex pheromone response in Drosophila
title_full_unstemmed Pre-imaginal conditioning alters adult sex pheromone response in Drosophila
title_short Pre-imaginal conditioning alters adult sex pheromone response in Drosophila
title_sort pre-imaginal conditioning alters adult sex pheromone response in drosophila
topic Animal Behavior
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164551/
https://www.ncbi.nlm.nih.gov/pubmed/30280017
http://dx.doi.org/10.7717/peerj.5585
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