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FK506 Attenuates the MRP1-Mediated Chemoresistant Phenotype in Glioblastoma Stem-Like Cells

Poor response to current treatments for glioblastoma has been attributed to the presence of glioblastoma stem-like cells (GSCs). GSCs are able to expel antitumor drugs to the extracellular medium using the multidrug resistance-associated protein 1 (MRP1) transporter. Tacrolimus (FK506) has been iden...

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Detalles Bibliográficos
Autores principales:	Torres, Ángelo, Arriagada, Valentina, Erices, José Ignacio, Toro, María de los Ángeles, Rocha, José Dellis, Niechi, Ignacio, Carrasco, Cristian, Oyarzún, Carlos, Quezada, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164673/ https://www.ncbi.nlm.nih.gov/pubmed/30208561 http://dx.doi.org/10.3390/ijms19092697

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