Uremic Toxins Activates Na/K-ATPase Oxidant Amplification Loop Causing Phenotypic Changes in Adipocytes in In Vitro Models

Background: Oxidant stress plays a key role in the development of chronic kidney disease (CKD). Experimental CKD leads to accumulation of uremic toxins (UT) in the circulation resulting in increased ROS production, which in turn, is known to activate the Na/K-ATPase/ROS amplification loop. Studies i...

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Detalles Bibliográficos
Autores principales: Bartlett, David E., Miller, Richard B., Thiesfeldt, Scott, Lakhani, Hari Vishal, Khanal, Tilak, D. Pratt, Rebecca, Cottrill, Cameron L., Klug, Rebecca L., Adkins, Nathaniel Seth, Bown, Paul C., Nease, D. Blaine, Shapiro, Joseph I., Sodhi, Komal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164729/
https://www.ncbi.nlm.nih.gov/pubmed/30201874
http://dx.doi.org/10.3390/ijms19092685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164729/
https://www.ncbi.nlm.nih.gov/pubmed/30201874
http://dx.doi.org/10.3390/ijms19092685

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