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Mechanism of Lakoochin A Inducing Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS and MAPKs Pathway

Malignant melanoma is developed from pigment-containing cells, melanocytes, and primarily found on the skin. Malignant melanoma still has a high mortality rate, which may imply a lack of therapeutic agents. Lakoochin A, a compound isolated from Artocarpus lakoocha and Artocarpus xanthocarpus, has an...

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Detalles Bibliográficos
Autores principales:	Peng, Kuo-Ti, Chiang, Yao-Chang, Ko, Horng-Huey, Chi, Pei-Ling, Tsai, Chia-Lan, Ko, Ming-I, Lee, Ming-Hsueh, Hsu, Lee-Fen, Lee, Chiang-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164788/ https://www.ncbi.nlm.nih.gov/pubmed/30200660 http://dx.doi.org/10.3390/ijms19092649

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