Rapid and Sensitive Determination of Vanillin Based on a Glassy Carbon Electrode Modified with Cu(2)O-Electrochemically Reduced Graphene Oxide Nanocomposite Film

A facile cuprous oxide nanoparticles functionalized electro-reduced graphene oxide modified glassy carbon electrode (denoted as Cu(2)O NPs-ERGO/GCE) was fabricated via a simple physical adsorption and electrochemical reduction approach. Cyclic voltammetry and second-order derivative linear scan voltammetry were used to investigate the electrocatalysis oxidation of vanillin on the Cu(2)O NPs-ERGO/GCE. The compound yielded a well-defined voltammetric response in 0.1 M H(2)SO(4) at 0.916 V (vs. saturated calomel electrode (SCE)). A linear calibration graph was obtained in the concentration range of 0.1 μM to 10 μM and 10 μM to 100 μM, while the detection limit (S/N = 3) is 10 nM. In addition, the Cu(2)O NPs-ERGO/GCE presented well anti-interference ability, stability, and reproducibility. It was used to detect vanillin sensitively and rapidly in different commercial food products, and the results were in agreement with the values obtained by high performance liquid chromatography.