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Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors
The late neurocognitive and psychosocial effects of treatment for pediatric brain tumor (PBT) represent important areas of clinical focus and ongoing research. Neurocognitive sequelae and associated problems with learning and socioemotional development negatively impact PBT survivors’ overall health...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164803/ https://www.ncbi.nlm.nih.gov/pubmed/30208602 http://dx.doi.org/10.3390/bioengineering5030073 |
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author | Stavinoha, Peter L. Askins, Martha A. Powell, Stephanie K. Pillay Smiley, Natasha Robert, Rhonda S. |
author_facet | Stavinoha, Peter L. Askins, Martha A. Powell, Stephanie K. Pillay Smiley, Natasha Robert, Rhonda S. |
author_sort | Stavinoha, Peter L. |
collection | PubMed |
description | The late neurocognitive and psychosocial effects of treatment for pediatric brain tumor (PBT) represent important areas of clinical focus and ongoing research. Neurocognitive sequelae and associated problems with learning and socioemotional development negatively impact PBT survivors’ overall health-related quality of life, educational attainment and employment rates. Multiple factors including tumor features and associated complications, treatment methods, individual protective and vulnerability factors and accessibility of environmental supports contribute to the neurocognitive and psychosocial outcomes in PBT survivors. Declines in overall measured intelligence are common and may persist years after treatment. Core deficits in attention, processing speed and working memory are postulated to underlie problems with overall intellectual development, academic achievement and career attainment. Additionally, psychological problems after PBT can include depression, anxiety and psychosocial adjustment issues. Several intervention paradigms are briefly described, though to date research on innovative, specific and effective interventions for neurocognitive late effects is still in its early stages. This article reviews the existing research for understanding PBT late effects and highlights the need for innovative research to enhance neurocognitive and psychosocial outcomes in PBT survivors. |
format | Online Article Text |
id | pubmed-6164803 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61648032018-10-11 Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors Stavinoha, Peter L. Askins, Martha A. Powell, Stephanie K. Pillay Smiley, Natasha Robert, Rhonda S. Bioengineering (Basel) Review The late neurocognitive and psychosocial effects of treatment for pediatric brain tumor (PBT) represent important areas of clinical focus and ongoing research. Neurocognitive sequelae and associated problems with learning and socioemotional development negatively impact PBT survivors’ overall health-related quality of life, educational attainment and employment rates. Multiple factors including tumor features and associated complications, treatment methods, individual protective and vulnerability factors and accessibility of environmental supports contribute to the neurocognitive and psychosocial outcomes in PBT survivors. Declines in overall measured intelligence are common and may persist years after treatment. Core deficits in attention, processing speed and working memory are postulated to underlie problems with overall intellectual development, academic achievement and career attainment. Additionally, psychological problems after PBT can include depression, anxiety and psychosocial adjustment issues. Several intervention paradigms are briefly described, though to date research on innovative, specific and effective interventions for neurocognitive late effects is still in its early stages. This article reviews the existing research for understanding PBT late effects and highlights the need for innovative research to enhance neurocognitive and psychosocial outcomes in PBT survivors. MDPI 2018-09-11 /pmc/articles/PMC6164803/ /pubmed/30208602 http://dx.doi.org/10.3390/bioengineering5030073 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Stavinoha, Peter L. Askins, Martha A. Powell, Stephanie K. Pillay Smiley, Natasha Robert, Rhonda S. Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors |
title | Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors |
title_full | Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors |
title_fullStr | Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors |
title_full_unstemmed | Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors |
title_short | Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors |
title_sort | neurocognitive and psychosocial outcomes in pediatric brain tumor survivors |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164803/ https://www.ncbi.nlm.nih.gov/pubmed/30208602 http://dx.doi.org/10.3390/bioengineering5030073 |
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