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Model Senescent Microglia Induce Disease Related Changes in α-Synuclein Expression and Activity
Aging is the most prominent risk factor for most neurodegenerative diseases. However, incorporating aging-related changes into models of neurodegeneration rarely occurs. One of the significant changes that occurs in the brain as we age is the shift in phenotype of the resident microglia population t...
Autores principales: | Angelova, Dafina M., Brown, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164966/ https://www.ncbi.nlm.nih.gov/pubmed/30071596 http://dx.doi.org/10.3390/biom8030067 |
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