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Model Senescent Microglia Induce Disease Related Changes in α-Synuclein Expression and Activity

Aging is the most prominent risk factor for most neurodegenerative diseases. However, incorporating aging-related changes into models of neurodegeneration rarely occurs. One of the significant changes that occurs in the brain as we age is the shift in phenotype of the resident microglia population t...

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Detalles Bibliográficos
Autores principales: Angelova, Dafina M., Brown, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164966/
https://www.ncbi.nlm.nih.gov/pubmed/30071596
http://dx.doi.org/10.3390/biom8030067

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