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Insights into the Influence of Specific Splicing Events on the Structural Organization of LRRK2

Leucine-rich repeat kinase 2 (LRRK2) is a large protein of unclear function. Rare mutations in the LRRK2 gene cause familial Parkinson’s disease (PD) and inflammatory bowel disease. Genome-wide association studies (GWAS) have revealed significant association of the abovementioned diseases at the LRR...

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Detalles Bibliográficos
Autores principales:	Vlachakis, Dimitrios, Labrou, Nikolaos E., Iliopoulos, Costas, Hardy, John, Lewis, Patrick A., Rideout, Hardy, Trabzuni, Daniah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165039/ https://www.ncbi.nlm.nih.gov/pubmed/30223621 http://dx.doi.org/10.3390/ijms19092784

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