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Therapeutic Peptide Amphiphile as a Drug Carrier with ATP-Triggered Release for Synergistic Effect, Improved Therapeutic Index, and Penetration of 3D Cancer Cell Spheroids

Despite the great progress in the field of drug delivery systems for cancer treatment over the last decade, many challenges still lie ahead, such as low drug loading, deep penetration of tumors, side effects, and the development of drug resistance. A class of cationic membrane lytic peptides has sho...

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Detalles Bibliográficos
Autores principales: Lu, Sheng, Zhao, Feng, Zhang, Qiuxin, Chen, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165277/
https://www.ncbi.nlm.nih.gov/pubmed/30223518
http://dx.doi.org/10.3390/ijms19092773