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Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy

Osteosarcoma (OS) is the most common bone tumor in children. Polyamines (PAs) are ubiquitous cations involved in many cell processes including tumor development, invasion and metastasis. In other pediatric cancer models, inhibition of the PA biosynthesis pathway with ornithine decarboxylase (ODC) in...

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Detalles Bibliográficos
Autores principales:	Weicht, Rebecca R., Schultz, Chad R., Geerts, Dirk, Uhl, Katie L., Bachmann, André S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165283/ https://www.ncbi.nlm.nih.gov/pubmed/30115881 http://dx.doi.org/10.3390/medsci6030065

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