Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy

Analyzing biomolecules is essential for disease diagnostics, food safety inspection, environmental monitoring and pharmaceutical development. Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for detecting biomolecules due to its high sensitivity, rapidness and specificity in identifying...

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Detalles Bibliográficos
Autores principales: Jia, Min, Li, Shenmiao, Zang, Liguo, Lu, Xiaonan, Zhang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165412/
https://www.ncbi.nlm.nih.gov/pubmed/30223597
http://dx.doi.org/10.3390/nano8090730
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author Jia, Min
Li, Shenmiao
Zang, Liguo
Lu, Xiaonan
Zhang, Hongyan
author_facet Jia, Min
Li, Shenmiao
Zang, Liguo
Lu, Xiaonan
Zhang, Hongyan
author_sort Jia, Min
collection PubMed
description Analyzing biomolecules is essential for disease diagnostics, food safety inspection, environmental monitoring and pharmaceutical development. Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for detecting biomolecules due to its high sensitivity, rapidness and specificity in identifying molecular structures. This review focuses on the SERS analysis of biomolecules originated from humans, animals, plants and microorganisms, combined with nanomaterials as SERS substrates and nanotags. Recent advances in SERS detection of target molecules were summarized with different detection strategies including label-free and label-mediated types. This comprehensive and critical summary of SERS analysis of biomolecules might help researchers from different scientific backgrounds spark new ideas and proposals.
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spelling pubmed-61654122018-10-10 Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy Jia, Min Li, Shenmiao Zang, Liguo Lu, Xiaonan Zhang, Hongyan Nanomaterials (Basel) Review Analyzing biomolecules is essential for disease diagnostics, food safety inspection, environmental monitoring and pharmaceutical development. Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for detecting biomolecules due to its high sensitivity, rapidness and specificity in identifying molecular structures. This review focuses on the SERS analysis of biomolecules originated from humans, animals, plants and microorganisms, combined with nanomaterials as SERS substrates and nanotags. Recent advances in SERS detection of target molecules were summarized with different detection strategies including label-free and label-mediated types. This comprehensive and critical summary of SERS analysis of biomolecules might help researchers from different scientific backgrounds spark new ideas and proposals. MDPI 2018-09-15 /pmc/articles/PMC6165412/ /pubmed/30223597 http://dx.doi.org/10.3390/nano8090730 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Jia, Min
Li, Shenmiao
Zang, Liguo
Lu, Xiaonan
Zhang, Hongyan
Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy
title Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy
title_full Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy
title_fullStr Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy
title_full_unstemmed Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy
title_short Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy
title_sort analysis of biomolecules based on the surface enhanced raman spectroscopy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165412/
https://www.ncbi.nlm.nih.gov/pubmed/30223597
http://dx.doi.org/10.3390/nano8090730
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