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Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that modulates gene expression following its binding and activation by structurally diverse chemicals. Species differences in AhR functionality have been observed, with the mouse AhR (mAhR) and human AhR (hAhR) exhibiting...

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Detalles Bibliográficos
Autores principales:	Faber, Samantha C., Soshilov, Anatoly A., Giani Tagliabue, Sara, Bonati, Laura, Denison, Michael S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165432/ https://www.ncbi.nlm.nih.gov/pubmed/30201897 http://dx.doi.org/10.3390/ijms19092692

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