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Endothelial AMP-Activated Kinase α1 Phosphorylates eNOS on Thr495 and Decreases Endothelial NO Formation

AMP-activated protein kinase (AMPK) is frequently reported to phosphorylate Ser1177 of the endothelial nitric-oxide synthase (eNOS), and therefore, is linked with a relaxing effect. However, previous studies failed to consistently demonstrate a major role for AMPK on eNOS-dependent relaxation. As AM...

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Detalles Bibliográficos
Autores principales:	Zippel, Nina, Loot, Annemarieke E., Stingl, Heike, Randriamboavonjy, Voahanginirina, Fleming, Ingrid, Fisslthaler, Beate
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165563/ https://www.ncbi.nlm.nih.gov/pubmed/30217073 http://dx.doi.org/10.3390/ijms19092753

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