When a Seemingly Harmless Prescription Turns into Toxicity

Valacyclovir neurotoxicity is commonly seen in the elderly and those with impaired renal function. Differential diagnosis can be challenging as a myriad of medical conditions, including herpes zoster virus associated encephalitis, may present in a similar fashion. We present a case of a 71-year-old...

Descripción completa

Detalles Bibliográficos
Autores principales: Azmaiparashvili, Zurab, Lo, Kevin Bryan, Habib, Nawal, Hsieh, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165624/
https://www.ncbi.nlm.nih.gov/pubmed/30305816
http://dx.doi.org/10.1155/2018/9724390
_version_ 1783359880031109120
author Azmaiparashvili, Zurab
Lo, Kevin Bryan
Habib, Nawal
Hsieh, Annie
author_facet Azmaiparashvili, Zurab
Lo, Kevin Bryan
Habib, Nawal
Hsieh, Annie
author_sort Azmaiparashvili, Zurab
collection PubMed
description Valacyclovir neurotoxicity is commonly seen in the elderly and those with impaired renal function. Differential diagnosis can be challenging as a myriad of medical conditions, including herpes zoster virus associated encephalitis, may present in a similar fashion. We present a case of a 71-year-old male who presented with altered mental status in the setting of recent herpes zoster eruption. His condition was attributed to valacyclovir neurotoxicity, and initiation of appropriate supportive therapy was met with complete resolution of symptoms and normalization of cognitive function.
format Online
Article
Text
id pubmed-6165624
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-61656242018-10-10 When a Seemingly Harmless Prescription Turns into Toxicity Azmaiparashvili, Zurab Lo, Kevin Bryan Habib, Nawal Hsieh, Annie Case Rep Med Case Report Valacyclovir neurotoxicity is commonly seen in the elderly and those with impaired renal function. Differential diagnosis can be challenging as a myriad of medical conditions, including herpes zoster virus associated encephalitis, may present in a similar fashion. We present a case of a 71-year-old male who presented with altered mental status in the setting of recent herpes zoster eruption. His condition was attributed to valacyclovir neurotoxicity, and initiation of appropriate supportive therapy was met with complete resolution of symptoms and normalization of cognitive function. Hindawi 2018-09-16 /pmc/articles/PMC6165624/ /pubmed/30305816 http://dx.doi.org/10.1155/2018/9724390 Text en Copyright © 2018 Zurab Azmaiparashvili et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Azmaiparashvili, Zurab
Lo, Kevin Bryan
Habib, Nawal
Hsieh, Annie
When a Seemingly Harmless Prescription Turns into Toxicity
title When a Seemingly Harmless Prescription Turns into Toxicity
title_full When a Seemingly Harmless Prescription Turns into Toxicity
title_fullStr When a Seemingly Harmless Prescription Turns into Toxicity
title_full_unstemmed When a Seemingly Harmless Prescription Turns into Toxicity
title_short When a Seemingly Harmless Prescription Turns into Toxicity
title_sort when a seemingly harmless prescription turns into toxicity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165624/
https://www.ncbi.nlm.nih.gov/pubmed/30305816
http://dx.doi.org/10.1155/2018/9724390
work_keys_str_mv AT azmaiparashvilizurab whenaseeminglyharmlessprescriptionturnsintotoxicity
AT lokevinbryan whenaseeminglyharmlessprescriptionturnsintotoxicity
AT habibnawal whenaseeminglyharmlessprescriptionturnsintotoxicity
AT hsiehannie whenaseeminglyharmlessprescriptionturnsintotoxicity

Ejemplares similares