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Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis
OBJECTIVE: The aim of this study was to compare the molecular profiling, including somatic mutation and somatic copy number variation (SCNV), between human epidermal growth factor receptor 2 (HER2)-positive (HER2+) and HER2-negative (HER2−) gastric cancer patients. PATIENTS AND METHODS: Tumor sample...
Autores principales: | Zhou, Chenfei, Feng, Xiaojing, Yuan, Fei, Ji, Jun, Shi, Min, Yu, Yingyan, Zhu, Zhenggang, Zhang, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165778/ https://www.ncbi.nlm.nih.gov/pubmed/30310315 http://dx.doi.org/10.2147/CMAR.S172710 |
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