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Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis

OBJECTIVE: The aim of this study was to compare the molecular profiling, including somatic mutation and somatic copy number variation (SCNV), between human epidermal growth factor receptor 2 (HER2)-positive (HER2+) and HER2-negative (HER2−) gastric cancer patients. PATIENTS AND METHODS: Tumor sample...

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Detalles Bibliográficos
Autores principales: Zhou, Chenfei, Feng, Xiaojing, Yuan, Fei, Ji, Jun, Shi, Min, Yu, Yingyan, Zhu, Zhenggang, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165778/
https://www.ncbi.nlm.nih.gov/pubmed/30310315
http://dx.doi.org/10.2147/CMAR.S172710

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