Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice

There is increasing clinical evidence to suggest a suppressive effect on hematopoiesis in myelodysplastic syndrome patients with iron overload. However, how iron overload influences hematopoiesis in myelodysplastic syndrome (MDS) remains unknown. Here, the RUNX1S291fs-transduced bone marrow mononucl...

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Detalles Bibliográficos
Autores principales: Jin, Xin, He, Xiaoyuan, Cao, Xiaoli, Xu, Ping, Xing, Yi, Sui, Songnan, Wang, Luqiao, Meng, Juanxia, Lu, Wenyi, Cui, Rui, Ni, Hongyan, Zhao, Mingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165791/
https://www.ncbi.nlm.nih.gov/pubmed/29903757
http://dx.doi.org/10.3324/haematol.2018.193128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165791/
https://www.ncbi.nlm.nih.gov/pubmed/29903757
http://dx.doi.org/10.3324/haematol.2018.193128

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