A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation

HLA antibodies are associated with refractoriness to platelet transfusion, leading to rapid platelet clearance, sometimes coinciding with clinical side effects such as fever and chills. The presence of HLA antibodies is not always manifested by clinical symptoms. It is currently unclear why refracto...

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Detalles Bibliográficos
Autores principales: Rijkers, Maaike, Saris, Anno, Heidt, Sebastiaan, Mulder, Arend, Porcelijn, Leendert, Claas, Frans H.J., Bierings, Ruben, Leebeek, Frank W.G., Jansen, A.J. Gerard, Vidarsson, Gestur, Voorberg, Jan, de Haas, Masja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165798/
https://www.ncbi.nlm.nih.gov/pubmed/29858387
http://dx.doi.org/10.3324/haematol.2018.189365

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