Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain

We previously found that the fifth epidermal growth factor-like domain of thrombomodulin (TME5) exerts cytoprotective and pro-angiogenic functions via G-protein coupled receptor 15 (GPR15). TME5 is comprised of three S-S bonds that divide it into three loops: A (TME5A), B (TME5B), and C (TME5C). Her...

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Detalles Bibliográficos
Autores principales: Wang, Xiangmin, Pan, Bin, Honda, Goichi, Wang, Xintao, Hashimoto, Yuko, Ohkawara, Hiroshi, Xu, Kailin, Zeng, Lingyu, Ikezoe, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165823/
https://www.ncbi.nlm.nih.gov/pubmed/29903766
http://dx.doi.org/10.3324/haematol.2017.184481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165823/
https://www.ncbi.nlm.nih.gov/pubmed/29903766
http://dx.doi.org/10.3324/haematol.2017.184481

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