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TRAF3 as a Multifaceted Regulator of B Lymphocyte Survival and Activation
The adaptor protein TNF receptor-associated factor 3 (TRAF3) serves as a powerful negative regulator in multiple aspects of B cell biology. Early in vitro studies in transformed cell lines suggested the potential of TRAF3 to inhibit signaling by its first identified binding receptor, CD40. However,...
Autores principales: | Bishop, Gail A., Stunz, Laura L., Hostager, Bruce S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165887/ https://www.ncbi.nlm.nih.gov/pubmed/30319624 http://dx.doi.org/10.3389/fimmu.2018.02161 |
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