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Design of the GutHeart—targeting gut microbiota to treat heart failure—trial: a Phase II, randomized clinical trial

AIMS: Heart failure (HF) is a multifactorial disease. Current treatments target only a fraction of the putative pathophysiological pathways. In patients with HF, reduced cardiac output and congestion cause increased gut wall permeability. It has been suggested that leakage of microbial products is d...

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Detalles Bibliográficos
Autores principales: Mayerhofer, Cristiane C.K., Awoyemi, Ayodeji O., Moscavitch, Samuel D., Lappegård, Knut Tore, Hov, Johannes R., Aukrust, Pål, Hovland, Anders, Lorenzo, Andrea, Halvorsen, Sigrun, Seljeflot, Ingebjørg, Gullestad, Lars, Trøseid, Marius, Broch, Kaspar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165929/
https://www.ncbi.nlm.nih.gov/pubmed/30088346
http://dx.doi.org/10.1002/ehf2.12332