Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity

Constitutive receptor activity/inverse agonism and functional selectivity/biased agonism are 2 concepts in contemporary pharmacology that have major implications for the use of drugs in medicine and research as well as for the processes of new drug development. Traditional receptor theory postulated...

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Detalles Bibliográficos
Autores principales: Berg, Kelly A, Clarke, William P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165953/
https://www.ncbi.nlm.nih.gov/pubmed/30085126
http://dx.doi.org/10.1093/ijnp/pyy071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165953/
https://www.ncbi.nlm.nih.gov/pubmed/30085126
http://dx.doi.org/10.1093/ijnp/pyy071

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