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Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer’s Disease Development

Alzheimer’s disease (AD) is the most common cause of dementia. Although genome-wide association study (GWAS) have reported hundreds of single-nucleotide polymorphisms (SNPs) and genes linked to AD, the mechanisms about how these SNPs modulate the development of AD remain largely unknown. In this stu...

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Detalles Bibliográficos
Autores principales: Liu, Changan, Chyr, Jacqueline, Zhao, Weiling, Xu, Yungang, Ji, Zhiwei, Tan, Hua, Soto, Claudio, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166008/
https://www.ncbi.nlm.nih.gov/pubmed/30319691
http://dx.doi.org/10.3389/fgene.2018.00410