RNA editing of Filamin A pre‐mRNA regulates vascular contraction and diastolic blood pressure

Epitranscriptomic events such as adenosine‐to‐inosine (A‐to‐I) RNA editing by ADAR can recode mRNAs to translate novel proteins. Editing of the mRNA that encodes actin crosslinking protein Filamin A (FLNA) mediates a Q‐to‐R transition in the interactive C‐terminal region. While FLNA editing is conse...

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Detalles Bibliográficos
Autores principales: Jain, Mamta, Mann, Tomer D, Stulić, Maja, Rao, Shailaja P, Kirsch, Andrijana, Pullirsch, Dieter, Strobl, Xué, Rath, Claus, Reissig, Lukas, Moreth, Kristin, Klein‐Rodewald, Tanja, Bekeredjian, Raffi, Gailus‐Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Pablik, Eleonore, Cimatti, Laura, Martin, David, Zinnanti, Jelena, Graier, Wolfgang F, Sibilia, Maria, Frank, Saša, Levanon, Erez Y, Jantsch, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166124/
https://www.ncbi.nlm.nih.gov/pubmed/30087110
http://dx.doi.org/10.15252/embj.201694813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166124/
https://www.ncbi.nlm.nih.gov/pubmed/30087110
http://dx.doi.org/10.15252/embj.201694813

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