Towards Personalized Medicine: An Improved De Novo Assembly Procedure for Early Detection of Drug Resistant HIV Minor Quasispecies in Patient Samples

The third-generation sequencing technology, PacBio, has shown an ability to sequence the HIV virus amplicons in their full length. The long read of PaBio offers a distinct advantage to comprehensively understand the virus evolution complexity at quasispecies level (i.e. maintaining linkage informati...

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Detalles Bibliográficos
Autores principales: Huang, Cindy, Sam, Vichetra, Du, Sophie, Le, Tuan, Fletcher, Anthony, Lau, William, Meyer, Kathleen, Asaki, Esther, Huang, Da Wei, Johnson, Calvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2018
Materias:
Software Model
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166399/
https://www.ncbi.nlm.nih.gov/pubmed/30310253
http://dx.doi.org/10.6026/97320630014449

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