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Beneficial coinfection can promote within-host viral diversity

In many viral infections, a large number of different genetic variants can coexist within a host, leading to more virulent infections that are better able to evolve antiviral resistance and adapt to new hosts. But how is this diversity maintained? Why do faster-growing variants not outcompete slower...

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Detalles Bibliográficos
Autores principales: Leeks, Asher, Segredo-Otero, Ernesto A, Sanjuán, Rafael, West, Stuart A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166523/
https://www.ncbi.nlm.nih.gov/pubmed/30288300
http://dx.doi.org/10.1093/ve/vey028