Cargando…

E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial

INTRODUCTION: Cigarette smoking by surgical patients is associated with increased complications. E-cigarettes have emerged as a potential smoking cessation tool. We sought to determine the feasibility and acceptability of e-cigarettes, compared to nicotine patch, for perioperative smoking cessation...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Susan M., Tenney, Rachel, Wallace, Arthur W., Arjomandi, Mehrdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166615/
https://www.ncbi.nlm.nih.gov/pubmed/30280019
http://dx.doi.org/10.7717/peerj.5609
_version_ 1783360073854091264
author Lee, Susan M.
Tenney, Rachel
Wallace, Arthur W.
Arjomandi, Mehrdad
author_facet Lee, Susan M.
Tenney, Rachel
Wallace, Arthur W.
Arjomandi, Mehrdad
author_sort Lee, Susan M.
collection PubMed
description INTRODUCTION: Cigarette smoking by surgical patients is associated with increased complications. E-cigarettes have emerged as a potential smoking cessation tool. We sought to determine the feasibility and acceptability of e-cigarettes, compared to nicotine patch, for perioperative smoking cessation in veterans. METHODS: Preoperative patients were randomized to either the nicotine patch group (n = 10) or the e-cigarette group (n = 20). Both groups were given a free 6-week supply in a tapering dose. All patients received brief counseling, a brochure on perioperative smoking cessation, and referral to the California Smokers’ Helpline. The primary outcome was rate of smoking cessation on day of surgery confirmed by exhaled carbon monoxide. Secondary outcomes included smoking habits, pulmonary function, adverse events, and satisfaction with the products on day of surgery and at 8-weeks follow-up. RESULTS: Biochemically verified smoking cessation on day of surgery was similar in both groups. Change in forced expiratory volume in one second (FEV1) was 592 ml greater in the e-cigarette group (95% CI [153–1,031] ml, p = 0.01) and change in forced expiratory volume in one second to forced vital capacity ratio (FEV1/FVC ratio) was 40.1% greater in the e-cigarette group (95% CI [18.2%–78.4%], p = 0.04). Satisfaction with the product was similar in both groups. DISCUSSION: E-cigarettes are a feasible tool for perioperative smoking cessation in veterans with quit rates comparable to nicotine replacement patch. Spirometry appears to be improved 8-weeks after initiating e-cigarettes compared to nicotine patch, possibly due to worse baseline spirometry and more smoking reduction in the e-cigarette group. An adequately powered study is recommended to determine if these results can be duplicated.
format Online
Article
Text
id pubmed-6166615
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher PeerJ Inc.
record_format MEDLINE/PubMed
spelling pubmed-61666152018-10-02 E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial Lee, Susan M. Tenney, Rachel Wallace, Arthur W. Arjomandi, Mehrdad PeerJ Anesthesiology and Pain Management INTRODUCTION: Cigarette smoking by surgical patients is associated with increased complications. E-cigarettes have emerged as a potential smoking cessation tool. We sought to determine the feasibility and acceptability of e-cigarettes, compared to nicotine patch, for perioperative smoking cessation in veterans. METHODS: Preoperative patients were randomized to either the nicotine patch group (n = 10) or the e-cigarette group (n = 20). Both groups were given a free 6-week supply in a tapering dose. All patients received brief counseling, a brochure on perioperative smoking cessation, and referral to the California Smokers’ Helpline. The primary outcome was rate of smoking cessation on day of surgery confirmed by exhaled carbon monoxide. Secondary outcomes included smoking habits, pulmonary function, adverse events, and satisfaction with the products on day of surgery and at 8-weeks follow-up. RESULTS: Biochemically verified smoking cessation on day of surgery was similar in both groups. Change in forced expiratory volume in one second (FEV1) was 592 ml greater in the e-cigarette group (95% CI [153–1,031] ml, p = 0.01) and change in forced expiratory volume in one second to forced vital capacity ratio (FEV1/FVC ratio) was 40.1% greater in the e-cigarette group (95% CI [18.2%–78.4%], p = 0.04). Satisfaction with the product was similar in both groups. DISCUSSION: E-cigarettes are a feasible tool for perioperative smoking cessation in veterans with quit rates comparable to nicotine replacement patch. Spirometry appears to be improved 8-weeks after initiating e-cigarettes compared to nicotine patch, possibly due to worse baseline spirometry and more smoking reduction in the e-cigarette group. An adequately powered study is recommended to determine if these results can be duplicated. PeerJ Inc. 2018-09-28 /pmc/articles/PMC6166615/ /pubmed/30280019 http://dx.doi.org/10.7717/peerj.5609 Text en ©2018 Lee et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Anesthesiology and Pain Management
Lee, Susan M.
Tenney, Rachel
Wallace, Arthur W.
Arjomandi, Mehrdad
E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial
title E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial
title_full E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial
title_fullStr E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial
title_full_unstemmed E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial
title_short E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial
title_sort e-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial
topic Anesthesiology and Pain Management
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166615/
https://www.ncbi.nlm.nih.gov/pubmed/30280019
http://dx.doi.org/10.7717/peerj.5609
work_keys_str_mv AT leesusanm ecigarettesversusnicotinepatchesforperioperativesmokingcessationapilotrandomizedtrial
AT tenneyrachel ecigarettesversusnicotinepatchesforperioperativesmokingcessationapilotrandomizedtrial
AT wallacearthurw ecigarettesversusnicotinepatchesforperioperativesmokingcessationapilotrandomizedtrial
AT arjomandimehrdad ecigarettesversusnicotinepatchesforperioperativesmokingcessationapilotrandomizedtrial