Pericyte-Specific Ninjurin1 Deletion Attenuates Vessel Maturation and Blood Flow Recovery in Hind Limb Ischemia

OBJECTIVE—: Angiogenesis, entire step from endothelial cells (ECs) sprouts to vascular maturation, is a critical response to ischemia. To form functional mature vessels, interactions between ECs and pericytes are essential. Ninj1 (ninjurin1) is an adhesion molecule that contributes to the pathogenes...

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Detalles Bibliográficos
Autores principales: Minoshima, Akiho, Kabara, Maki, Matsuki, Motoki, Yoshida, Yuri, Kano, Kohei, Tomita, Yui, Hayasaka, Taiki, Horiuchi, Kiwamu, Saito, Yukihiro, Aonuma, Tatsuya, Nishimura, Masato, Maruyama, Keisuke, Nakagawa, Naoki, Sawada, Jun, Takehara, Naofumi, Hasebe, Naoyuki, Kawabe, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166707/
https://www.ncbi.nlm.nih.gov/pubmed/30354207
http://dx.doi.org/10.1161/ATVBAHA.118.311375

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