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Structure–function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-κB

The closely related type III secretion system zinc metalloprotease effector proteins GtgA, GogA, and PipA are translocated into host cells during Salmonella infection. They then cleave nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) transcription factor subunits, dampening activat...

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Detalles Bibliográficos
Autores principales:	Jennings, Elliott, Esposito, Diego, Rittinger, Katrin, Thurston, Teresa L. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Editors' Picks
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166728/ https://www.ncbi.nlm.nih.gov/pubmed/30049795 http://dx.doi.org/10.1074/jbc.RA118.004255

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