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Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages

Genome-wide investigations of host–pathogen interactions are often limited by analyses of mixed populations of infected and uninfected cells, which lower sensitivity and accuracy. To overcome these obstacles and identify key mechanisms by which Zika virus (ZIKV) manipulates host responses, we develo...

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Detalles Bibliográficos
Autores principales: Carlin, Aaron F., Vizcarra, Edward A., Branche, Emilie, Viramontes, Karla M., Suarez-Amaran, Lester, Ley, Klaus, Heinz, Sven, Benner, Christopher, Shresta, Sujan, Glass, Christopher K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166801/
https://www.ncbi.nlm.nih.gov/pubmed/30206152
http://dx.doi.org/10.1073/pnas.1807690115