Cargando…
Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages
Genome-wide investigations of host–pathogen interactions are often limited by analyses of mixed populations of infected and uninfected cells, which lower sensitivity and accuracy. To overcome these obstacles and identify key mechanisms by which Zika virus (ZIKV) manipulates host responses, we develo...
Autores principales: | Carlin, Aaron F., Vizcarra, Edward A., Branche, Emilie, Viramontes, Karla M., Suarez-Amaran, Lester, Ley, Klaus, Heinz, Sven, Benner, Christopher, Shresta, Sujan, Glass, Christopher K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166801/ https://www.ncbi.nlm.nih.gov/pubmed/30206152 http://dx.doi.org/10.1073/pnas.1807690115 |
Ejemplares similares
-
Gene expression distribution deconvolution in single-cell RNA sequencing
por: Wang, Jingshu, et al.
Publicado: (2018) -
An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity
por: Schmidt, Nora, et al.
Publicado: (2019) -
High-resolution structures of HIV-1 Gag cleavage mutants determine structural switch for virus maturation
por: Mattei, Simone, et al.
Publicado: (2018) -
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages
por: Muse, Evan D., et al.
Publicado: (2018) -
A hypothesis linking the energy demand of the brain to obesity risk
por: Kuzawa, Christopher W., et al.
Publicado: (2019)