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Functional characterization of reappearing B cells after anti-CD20 treatment of CNS autoimmune disease
The anti-CD20 antibody ocrelizumab, approved for treatment of multiple sclerosis, leads to rapid elimination of B cells from the blood. The extent of B cell depletion and kinetics of their recovery in different immune compartments is largely unknown. Here, we studied how anti-CD20 treatment influenc...
Autores principales: | Häusler, Darius, Häusser-Kinzel, Silke, Feldmann, Linda, Torke, Sebastian, Lepennetier, Gildas, Bernard, Claude C. A., Zamvil, Scott S., Brück, Wolfgang, Lehmann-Horn, Klaus, Weber, Martin S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166805/ https://www.ncbi.nlm.nih.gov/pubmed/30194232 http://dx.doi.org/10.1073/pnas.1810470115 |
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