Cargando…

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

The activation of natural killer (NK) cells depends on a change in the balance of signals from inhibitory and activating receptors. The activation threshold values of NK cells are thought to be set by engagement of inhibitory receptors during development. Here, we found that the activating receptor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jelenčić, Vedrana, Šestan, Marko, Kavazović, Inga, Lenartić, Maja, Marinović, Sonja, Holmes, Tim D., Prchal-Murphy, Michaela, Lisnić, Berislav, Sexl, Veronika, Bryceson, Yenan T., Wensveen, Felix M., Polić, Bojan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166863/ https://www.ncbi.nlm.nih.gov/pubmed/30224819 http://dx.doi.org/10.1038/s41590-018-0209-9

Ejemplares similares

Largely preserved functionality after the combined loss of NKG2D, NCR1 and CD16 demonstrates the remarkable plasticity of NK cell responsiveness
por: Imširović, Vanna, et al.
Publicado: (2023)

NKG2D: A Master Regulator of Immune Cell Responsiveness
por: Wensveen, Felix M., et al.
Publicado: (2018)

NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells
por: Babic, Marina, et al.
Publicado: (2020)

Regulation of immune cell function and differentiation by the NKG2D receptor
por: Zafirova, Biljana, et al.
Publicado: (2011)

Cheating the Hunger Games; Mechanisms Controlling Clonal Diversity of CD8 Effector and Memory Populations
por: Kavazović, Inga, et al.
Publicado: (2018)

Efficient Killing of Murine Pluripotent Stem Cells by Natural Killer (NK) Cells Requires Activation by Cytokines and Partly Depends on the Activating NK Receptor NKG2D
por: Gröschel, Carina, et al.
Publicado: (2017)

Activation of NK Cells by an Endocytosed Receptor for Soluble HLA-G
por: Rajagopalan, Sumati, et al.
Publicado: (2006)

Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells
por: Bryceson, Yenan T., et al.
Publicado: (2005)

Rough operators: sphingomyelinase inhibitors spike NK cells to kill cancer
por: Carlsten, Mattias, et al.
Publicado: (2023)

Chronic NKG2D Engagement In Vivo Differentially Impacts NK Cell Responsiveness by Activating NK Receptors
por: Koch, Christine, et al.
Publicado: (2017)

Epigenetic regulation of NK cell differentiation and effector functions
por: Cichocki, Frank, et al.
Publicado: (2013)

Identification of putative novel O-glycosylations in the NK killer receptor Ncr1 essential for its activity
por: Glasner, Ariella, et al.
Publicado: (2015)

Editorial: Molecular and Cellular Pathways in NK Cell Development
por: Sitnicka, Ewa, et al.
Publicado: (2020)

Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2
por: Prinz, Daniela, et al.
Publicado: (2020)

The NK cell checkpoint NKG2A maintains expansion capacity of human NK cells
por: Kaulfuss, Meike, et al.
Publicado: (2023)

Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis
por: Molfetta, Rosa, et al.
Publicado: (2017)

The Murine Natural Cytotoxic Receptor NKp46/NCR1 Controls TRAIL Protein Expression in NK Cells and ILC1s
por: Sheppard, Sam, et al.
Publicado: (2018)

NK cells negatively regulate CD8 T cells via natural cytotoxicity receptor (NCR) 1 during LCMV infection
por: Pallmer, Katharina, et al.
Publicado: (2019)

LIR‐1 educates expanded human NK cells and defines a unique antitumor NK cell subset with potent antibody‐dependent cellular cytotoxicity
por: Leijonhufvud, Caroline, et al.
Publicado: (2021)

BPTF inhibits NK cell activity and the abundance of natural cytotoxicity receptor co-ligands
por: Mayes, Kimberly, et al.
Publicado: (2017)

Selective reconstitution of IFN‑γ gene function in Ncr1(+) NK cells is sufficient to control systemic vaccinia virus infection
por: Borst, Katharina, et al.
Publicado: (2020)

NKG2D and DNAM-1 activating receptors and their ligands in NK-T cell interactions: role in the NK cell-mediated negative regulation of T cell responses
por: Zingoni, Alessandra, et al.
Publicado: (2013)

CD56(dim)CD57(+)NKG2C(+) NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT
por: Cichocki, Frank, et al.
Publicado: (2015)

Bone Marrow Allograft Rejection Mediated by a Novel Murine NK Receptor, NKG2I
por: Koike, Junzo, et al.
Publicado: (2004)

Pseudorabies Virus Infection Causes Downregulation of Ligands for the Activating NK Cell Receptor NKG2D
por: Denaeghel, Sofie, et al.
Publicado: (2021)

NKG2C+ NK Cells for Immunotherapy of Glioblastoma Multiforme
por: Murad, Shafiq, et al.
Publicado: (2022)

NKG2D is a Key Receptor for Recognition of Bladder Cancer Cells by IL-2-Activated NK Cells and BCG Promotes NK Cell Activation
por: García-Cuesta, Eva María, et al.
Publicado: (2015)

Expression of the inhibitory receptor NKG2A correlates with increased liver and splenic NK cell response to activating receptor engagement
por: Meyer, Claire E., et al.
Publicado: (2017)

The Natural Cytotoxicity Receptor NKp44 (NCR2, CD336) Is Expressed on the Majority of Porcine NK Cells Ex Vivo Without Stimulation
por: Mair, Kerstin H., et al.
Publicado: (2022)

Unexpected role of STAT1 serine727 for NK cell function
por: Putz, Eva M, et al.
Publicado: (2009)

The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors
por: Železnjak, Jelena, et al.
Publicado: (2019)

Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity
por: Kavazović, Inga, et al.
Publicado: (2020)

Characterization of NCR1+ cells residing in lymphoid tissues in the gut of lambs indicates that the majority are NK cells
por: Olsen, Line, et al.
Publicado: (2013)

STAT1 Ser727 – key regulator for NK cell-mediated cytotoxicity and tumor surveillance
por: Putz, Eva M, et al.
Publicado: (2008)

Dynamic Shift from CD85j/ILT-2 to NKG2D NK Receptor Expression Pattern on Human Decidual NK during the First Trimester of Pregnancy
por: Marlin, Romain, et al.
Publicado: (2012)

Analysis of the Expression of Surface Receptors on NK Cells and NKG2D on Immunocytes in Peripheral Blood of Patients with Nasopharyngeal Carcinoma
por: Xu, Yuanji, et al.
Publicado: (2018)

Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells
por: Rožmanić, Carmen, et al.
Publicado: (2023)

Polyclonal Expansion of NKG2C(+) NK Cells in TAP-Deficient Patients
por: Béziat, Vivien, et al.
Publicado: (2015)

NKG2A is a NK cell exhaustion checkpoint for HCV persistence
por: Zhang, Chao, et al.
Publicado: (2019)

High Metabolic Function and Resilience of NKG2A-Educated NK Cells
por: Highton, Andrew J., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_571p3snqpphlfc21s122kvi0ua