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The DEAD-box RNA-binding protein DDX6 regulates parental RNA decay for cellular reprogramming to pluripotency

Cellular transitions and differentiation processes require mRNAs supporting the new phenotype but also the clearance of existing mRNAs for the parental phenotype. Cellular reprogramming from fibroblasts to induced pluripotent stem cells (iPSCs) occurs at the early stage of mesenchymal epithelial tra...

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Detalles Bibliográficos
Autores principales: Kami, Daisuke, Kitani, Tomoya, Nakamura, Akihiro, Wakui, Naoki, Mizutani, Rena, Ohue, Masahito, Kametani, Fuyuki, Akimitsu, Nobuyoshi, Gojo, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166933/
https://www.ncbi.nlm.nih.gov/pubmed/30273347
http://dx.doi.org/10.1371/journal.pone.0203708