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The DEAD-box RNA-binding protein DDX6 regulates parental RNA decay for cellular reprogramming to pluripotency
Cellular transitions and differentiation processes require mRNAs supporting the new phenotype but also the clearance of existing mRNAs for the parental phenotype. Cellular reprogramming from fibroblasts to induced pluripotent stem cells (iPSCs) occurs at the early stage of mesenchymal epithelial tra...
Autores principales: | Kami, Daisuke, Kitani, Tomoya, Nakamura, Akihiro, Wakui, Naoki, Mizutani, Rena, Ohue, Masahito, Kametani, Fuyuki, Akimitsu, Nobuyoshi, Gojo, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166933/ https://www.ncbi.nlm.nih.gov/pubmed/30273347 http://dx.doi.org/10.1371/journal.pone.0203708 |
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