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A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease

BACKGROUND: Patients with chronic kidney disease (CKD) have increased risk of development of end-stage renal disease (ESRD) and early mortality. Fibrosis is the central pathogenic process in CKD and is caused by dysregulated extracellular matrix (ECM) remodeling. The laminin γ1 chain (LAMC1) is a co...

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Detalles Bibliográficos
Autores principales:	Holm Nielsen, Signe, Guldager Kring Rasmussen, Daniel, Brix, Susanne, Fenton, Anthony, Jesky, Mark, Ferro, Charles J., Karsdal, Morten, Genovese, Federica, Cockwell, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166934/ https://www.ncbi.nlm.nih.gov/pubmed/30273365 http://dx.doi.org/10.1371/journal.pone.0204239

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