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A stochastic model of myeloid cell lineages in hematopoiesis and pathway mutations in acute myeloid leukemia
A model for hematopoiesis is presented that explicitly includes the erythrocyte, granulocyte, and thrombocyte lineages and their common precursors. A small number of stem cells proliferate and differentiate through different compartments to produce the vast number of blood cells needed every day. Gr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166954/ https://www.ncbi.nlm.nih.gov/pubmed/30273383 http://dx.doi.org/10.1371/journal.pone.0204393 |