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Diagnostic value of STAF score in combination with D-dimer in cardioembolism

The aim of this study was to evaluate the diagnostic value of the Score for the Targeting of Atrial Fibrillation (STAF) in combination with the serum D-dimer (DD) levels in cardioembolism(CE).This study was a retrospective case-onlystudy, consecutively including patients with acute ischemic stroke....

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Autores principales: Liu, Li-Bin, Guo, Ya-Dong, Xu, An-Ding, Zhong, Jie-Xi, Zhuo, Wen-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166956/
https://www.ncbi.nlm.nih.gov/pubmed/30273382
http://dx.doi.org/10.1371/journal.pone.0204838
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author Liu, Li-Bin
Guo, Ya-Dong
Xu, An-Ding
Zhong, Jie-Xi
Zhuo, Wen-Yan
author_facet Liu, Li-Bin
Guo, Ya-Dong
Xu, An-Ding
Zhong, Jie-Xi
Zhuo, Wen-Yan
author_sort Liu, Li-Bin
collection PubMed
description The aim of this study was to evaluate the diagnostic value of the Score for the Targeting of Atrial Fibrillation (STAF) in combination with the serum D-dimer (DD) levels in cardioembolism(CE).This study was a retrospective case-onlystudy, consecutively including patients with acute ischemic stroke. All patients were evaluated following the STAF scoring criteria and were classified according to the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) etiology classification criteria. A total of 317 patients were enrolled, including 37 CE cases (11.67%). STAF ≥5 showed a sensitivity of 89% and a specificity of 91% for the diagnosis of CE, whereas DD >791.30 ng/mL had a sensitivity of 58% and a specificity of 78%. When the STAF was used in combination with the DD level, the sensitivity was 95%, and the specificity was 100%.STAF score is an excellent tool for the diagnosis of CE when combined with DD, and can facilitate the etiological classification of acute ischemic stroke.
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spelling pubmed-61669562018-10-19 Diagnostic value of STAF score in combination with D-dimer in cardioembolism Liu, Li-Bin Guo, Ya-Dong Xu, An-Ding Zhong, Jie-Xi Zhuo, Wen-Yan PLoS One Research Article The aim of this study was to evaluate the diagnostic value of the Score for the Targeting of Atrial Fibrillation (STAF) in combination with the serum D-dimer (DD) levels in cardioembolism(CE).This study was a retrospective case-onlystudy, consecutively including patients with acute ischemic stroke. All patients were evaluated following the STAF scoring criteria and were classified according to the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) etiology classification criteria. A total of 317 patients were enrolled, including 37 CE cases (11.67%). STAF ≥5 showed a sensitivity of 89% and a specificity of 91% for the diagnosis of CE, whereas DD >791.30 ng/mL had a sensitivity of 58% and a specificity of 78%. When the STAF was used in combination with the DD level, the sensitivity was 95%, and the specificity was 100%.STAF score is an excellent tool for the diagnosis of CE when combined with DD, and can facilitate the etiological classification of acute ischemic stroke. Public Library of Science 2018-10-01 /pmc/articles/PMC6166956/ /pubmed/30273382 http://dx.doi.org/10.1371/journal.pone.0204838 Text en © 2018 Liu et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Liu, Li-Bin
Guo, Ya-Dong
Xu, An-Ding
Zhong, Jie-Xi
Zhuo, Wen-Yan
Diagnostic value of STAF score in combination with D-dimer in cardioembolism
title Diagnostic value of STAF score in combination with D-dimer in cardioembolism
title_full Diagnostic value of STAF score in combination with D-dimer in cardioembolism
title_fullStr Diagnostic value of STAF score in combination with D-dimer in cardioembolism
title_full_unstemmed Diagnostic value of STAF score in combination with D-dimer in cardioembolism
title_short Diagnostic value of STAF score in combination with D-dimer in cardioembolism
title_sort diagnostic value of staf score in combination with d-dimer in cardioembolism
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166956/
https://www.ncbi.nlm.nih.gov/pubmed/30273382
http://dx.doi.org/10.1371/journal.pone.0204838
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