Cytoprotective effect of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) is mediated by the inhibition of BAK-dependent mitochondrial apoptosis pathway

The inhibitory mechanism of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) against apoptosis induced by the microtubule-damaging agents (MDAs), nocodazole (NOC) and 2-methoxyestradiol (2-MeO-E(2)), or a DNA-damaging agent (DDA), camptothecin (CPT) were investigated in human Jurkat T...

Descripción completa

Detalles Bibliográficos
Autores principales: Jun, Do Youn, Jang, Won Young, Kim, Ki Yun, Woo, Mi Hee, Kim, Young Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166973/
https://www.ncbi.nlm.nih.gov/pubmed/30273361
http://dx.doi.org/10.1371/journal.pone.0204585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166973/
https://www.ncbi.nlm.nih.gov/pubmed/30273361
http://dx.doi.org/10.1371/journal.pone.0204585

Ejemplares similares