Transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus

Gene therapy that targets the pancreas and intestines with delivery systems using nano-sized carriers such as viral and non-viral vectors could improve the control of blood glucose levels, resulting in an improved prognosis for patients with diabetes mellitus. Allogenic pancreatic islet cell transpl...

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Detalles Bibliográficos
Autores principales: Ito, Kiyonori, Ookawara, Susumu, Ishibashi, Kenichi, Morishita, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167029/
https://www.ncbi.nlm.nih.gov/pubmed/30410709
http://dx.doi.org/10.1080/20022727.2017.1341758
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author Ito, Kiyonori
Ookawara, Susumu
Ishibashi, Kenichi
Morishita, Yoshiyuki
author_facet Ito, Kiyonori
Ookawara, Susumu
Ishibashi, Kenichi
Morishita, Yoshiyuki
author_sort Ito, Kiyonori
collection PubMed
description Gene therapy that targets the pancreas and intestines with delivery systems using nano-sized carriers such as viral and non-viral vectors could improve the control of blood glucose levels, resulting in an improved prognosis for patients with diabetes mellitus. Allogenic pancreatic islet cell transplantations using such delivery systems have been developed as therapeutic options for diabetes mellitus. This review focuses on transgenes and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus.
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spelling pubmed-61670292018-10-02 Transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus Ito, Kiyonori Ookawara, Susumu Ishibashi, Kenichi Morishita, Yoshiyuki Nano Rev Exp Review Article Gene therapy that targets the pancreas and intestines with delivery systems using nano-sized carriers such as viral and non-viral vectors could improve the control of blood glucose levels, resulting in an improved prognosis for patients with diabetes mellitus. Allogenic pancreatic islet cell transplantations using such delivery systems have been developed as therapeutic options for diabetes mellitus. This review focuses on transgenes and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus. Taylor & Francis 2017-06-25 /pmc/articles/PMC6167029/ /pubmed/30410709 http://dx.doi.org/10.1080/20022727.2017.1341758 Text en © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ito, Kiyonori
Ookawara, Susumu
Ishibashi, Kenichi
Morishita, Yoshiyuki
Transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus
title Transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus
title_full Transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus
title_fullStr Transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus
title_full_unstemmed Transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus
title_short Transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus
title_sort transgene and islet cell delivery systems using nano-sized carriers for the treatment of diabetes mellitus
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167029/
https://www.ncbi.nlm.nih.gov/pubmed/30410709
http://dx.doi.org/10.1080/20022727.2017.1341758
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