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Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell

The structural modeling and representation of cells is a complex task as different microscopic, spectroscopic and other information resources have to be combined to achieve a three-dimensional representation with high accuracy. Moreover, to provide an appropriate spatial representation of the cell,...

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Autores principales: Biere, Niklas, Ghaffar, Mehmood, Doebbe, Anja, Jäger, Daniel, Rothe, Nils, Friedrich, Benjamin M., Hofestädt, Ralf, Schreiber, Falk, Kruse, Olaf, Sommer, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167046/
https://www.ncbi.nlm.nih.gov/pubmed/30001212
http://dx.doi.org/10.1515/jib-2018-0003
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author Biere, Niklas
Ghaffar, Mehmood
Doebbe, Anja
Jäger, Daniel
Rothe, Nils
Friedrich, Benjamin M.
Hofestädt, Ralf
Schreiber, Falk
Kruse, Olaf
Sommer, Björn
author_facet Biere, Niklas
Ghaffar, Mehmood
Doebbe, Anja
Jäger, Daniel
Rothe, Nils
Friedrich, Benjamin M.
Hofestädt, Ralf
Schreiber, Falk
Kruse, Olaf
Sommer, Björn
author_sort Biere, Niklas
collection PubMed
description The structural modeling and representation of cells is a complex task as different microscopic, spectroscopic and other information resources have to be combined to achieve a three-dimensional representation with high accuracy. Moreover, to provide an appropriate spatial representation of the cell, a stereoscopic 3D (S3D) visualization is favorable. In this work, a structural cell model is created by combining information from various light microscopic and electron microscopic images as well as from publication-related data. At the mesoscopic level each cell component is presented with special structural and visual properties; at the molecular level a cell membrane composition and the underlying modeling method are discussed; and structural information is correlated with those at the functional level (represented by simplified energy-producing metabolic pathways). The organism used as an example is the unicellular Chlamydomonas reinhardtii, which might be important in future alternative energy production processes. Based on the 3D model, an educative S3D animation was created which was shown at conferences. The complete workflow was accomplished by using the open source 3D modeling software Blender. The discussed project including the animation is available from: http://Cm5.CELLmicrocosmos.org
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spelling pubmed-61670462019-01-28 Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell Biere, Niklas Ghaffar, Mehmood Doebbe, Anja Jäger, Daniel Rothe, Nils Friedrich, Benjamin M. Hofestädt, Ralf Schreiber, Falk Kruse, Olaf Sommer, Björn J Integr Bioinform Research Articles The structural modeling and representation of cells is a complex task as different microscopic, spectroscopic and other information resources have to be combined to achieve a three-dimensional representation with high accuracy. Moreover, to provide an appropriate spatial representation of the cell, a stereoscopic 3D (S3D) visualization is favorable. In this work, a structural cell model is created by combining information from various light microscopic and electron microscopic images as well as from publication-related data. At the mesoscopic level each cell component is presented with special structural and visual properties; at the molecular level a cell membrane composition and the underlying modeling method are discussed; and structural information is correlated with those at the functional level (represented by simplified energy-producing metabolic pathways). The organism used as an example is the unicellular Chlamydomonas reinhardtii, which might be important in future alternative energy production processes. Based on the 3D model, an educative S3D animation was created which was shown at conferences. The complete workflow was accomplished by using the open source 3D modeling software Blender. The discussed project including the animation is available from: http://Cm5.CELLmicrocosmos.org De Gruyter 2018-07-11 /pmc/articles/PMC6167046/ /pubmed/30001212 http://dx.doi.org/10.1515/jib-2018-0003 Text en ©2018, Niklas Biere et al., published by DeGruyter, Berlin/Boston http://creativecommons.org/licenses/by-nc-nd/4.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
spellingShingle Research Articles
Biere, Niklas
Ghaffar, Mehmood
Doebbe, Anja
Jäger, Daniel
Rothe, Nils
Friedrich, Benjamin M.
Hofestädt, Ralf
Schreiber, Falk
Kruse, Olaf
Sommer, Björn
Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell
title Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell
title_full Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell
title_fullStr Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell
title_full_unstemmed Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell
title_short Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell
title_sort heuristic modeling and 3d stereoscopic visualization of a chlamydomonas reinhardtii cell
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167046/
https://www.ncbi.nlm.nih.gov/pubmed/30001212
http://dx.doi.org/10.1515/jib-2018-0003
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