Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome

Medically refractory, severe, cholestasis‐induced pruritus in Alagille syndrome may be improved by surgical interruption of the enterohepatic circulation. This multicenter trial (NCT02057692) tested the hypothesis that the intestinal bile acid transport inhibitor maralixibat would similarly reduce p...

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Detalles Bibliográficos
Autores principales: Shneider, Benjamin L., Spino, Cathie, Kamath, Binita M., Magee, John C., Bass, Lee M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Murray, Karen F., Loomes, Kathleen M., Rosenthal, Philip, Karpen, Saul J., Leung, Daniel H., Guthery, Stephen L., Thomas, Danny, Sherker, Averell H., Sokol, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167076/
https://www.ncbi.nlm.nih.gov/pubmed/30288474
http://dx.doi.org/10.1002/hep4.1244

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