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Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue

BACKGROUND: Early detection of oral cancer is the most effective means of reducing morbidity, complexity, and extent of treatment. This study evaluated the clinicopathological profile of epidermoid carcinoma of the tongue, including treatment and survival. MATERIAL AND METHODS: This observational, r...

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Autores principales: Nóbrega, Thamirys-Dantas, Queiroz, Salomão-Israel-Monteiro-Lourenço, Santos, Edilmar-de Moura, Costa, Antônio-de Lisboa-Lopes, Pereira-Pinto, Leão, de Souza, Lélia-Batista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167096/
https://www.ncbi.nlm.nih.gov/pubmed/30148462
http://dx.doi.org/10.4317/medoral.22421
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author Nóbrega, Thamirys-Dantas
Queiroz, Salomão-Israel-Monteiro-Lourenço
Santos, Edilmar-de Moura
Costa, Antônio-de Lisboa-Lopes
Pereira-Pinto, Leão
de Souza, Lélia-Batista
author_facet Nóbrega, Thamirys-Dantas
Queiroz, Salomão-Israel-Monteiro-Lourenço
Santos, Edilmar-de Moura
Costa, Antônio-de Lisboa-Lopes
Pereira-Pinto, Leão
de Souza, Lélia-Batista
author_sort Nóbrega, Thamirys-Dantas
collection PubMed
description BACKGROUND: Early detection of oral cancer is the most effective means of reducing morbidity, complexity, and extent of treatment. This study evaluated the clinicopathological profile of epidermoid carcinoma of the tongue, including treatment and survival. MATERIAL AND METHODS: This observational, retrospective cross-sectional study evaluated patients with squamous cell carcinoma of the tongue treated at the Dr. Luiz Antônio Hospital, Natal, Brazil, from January 2001 to December 2011. Survival variables were calculated using the Kaplan-Meier method and compared by log rank tests. RESULTS: Of the 412 patients diagnosed in this period, 298 (72.3%) were men; their mean age was 60.5 years, and 69.2% were diagnosed with stage III/IV tumours. Improved survival was associated with early stage diagnosis, absence of affected lymph nodes at diagnosis, and treatment with surgery alone. CONCLUSIONS: Late stage diagnosis of oral cancer negatively affects patient survival. In addition, the general public should be made aware of the prognostic factors for oral SCC of the tongue and of the importance of periodic examinations of the oral cavity. Key words:Mouth neoplasms, tongue neoplasms, carcinoma, squamous cell, survival analysis.
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spelling pubmed-61670962018-10-04 Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue Nóbrega, Thamirys-Dantas Queiroz, Salomão-Israel-Monteiro-Lourenço Santos, Edilmar-de Moura Costa, Antônio-de Lisboa-Lopes Pereira-Pinto, Leão de Souza, Lélia-Batista Med Oral Patol Oral Cir Bucal Research BACKGROUND: Early detection of oral cancer is the most effective means of reducing morbidity, complexity, and extent of treatment. This study evaluated the clinicopathological profile of epidermoid carcinoma of the tongue, including treatment and survival. MATERIAL AND METHODS: This observational, retrospective cross-sectional study evaluated patients with squamous cell carcinoma of the tongue treated at the Dr. Luiz Antônio Hospital, Natal, Brazil, from January 2001 to December 2011. Survival variables were calculated using the Kaplan-Meier method and compared by log rank tests. RESULTS: Of the 412 patients diagnosed in this period, 298 (72.3%) were men; their mean age was 60.5 years, and 69.2% were diagnosed with stage III/IV tumours. Improved survival was associated with early stage diagnosis, absence of affected lymph nodes at diagnosis, and treatment with surgery alone. CONCLUSIONS: Late stage diagnosis of oral cancer negatively affects patient survival. In addition, the general public should be made aware of the prognostic factors for oral SCC of the tongue and of the importance of periodic examinations of the oral cavity. Key words:Mouth neoplasms, tongue neoplasms, carcinoma, squamous cell, survival analysis. Medicina Oral S.L. 2018-09 2018-09-28 /pmc/articles/PMC6167096/ /pubmed/30148462 http://dx.doi.org/10.4317/medoral.22421 Text en Copyright: © 2018 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Nóbrega, Thamirys-Dantas
Queiroz, Salomão-Israel-Monteiro-Lourenço
Santos, Edilmar-de Moura
Costa, Antônio-de Lisboa-Lopes
Pereira-Pinto, Leão
de Souza, Lélia-Batista
Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue
title Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue
title_full Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue
title_fullStr Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue
title_full_unstemmed Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue
title_short Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue
title_sort clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167096/
https://www.ncbi.nlm.nih.gov/pubmed/30148462
http://dx.doi.org/10.4317/medoral.22421
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