Radiation-related superficial oral mucoceles: An under-recognized acute toxicity in head and neck cancer patients

BACKGROUND: Acute toxicity is usually defined as adverse changes occurring immediately or a short time after the start of oncological treatment. MATERIAL AND METHODS: Cross-sectional retrospective study performed with head and neck cancer patients who underwent radiotherapy from 2013 to 2016. RESULT...

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Detalles Bibliográficos
Autores principales: Prado-Ribeiro, Ana-Carolina, Santos-Silva, Alan-Roger, Faria, Karina-Morais, Silva, Wagner-Gomes, Simonato, Luciana-Estevam, Moutinho, Karina, Brandão, Thais-Bianca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167097/
https://www.ncbi.nlm.nih.gov/pubmed/30148465
http://dx.doi.org/10.4317/medoral.22470
Descripción
Sumario:BACKGROUND: Acute toxicity is usually defined as adverse changes occurring immediately or a short time after the start of oncological treatment. MATERIAL AND METHODS: Cross-sectional retrospective study performed with head and neck cancer patients who underwent radiotherapy from 2013 to 2016. RESULTS: Ten (1.2%) patients developed SOMs during radiotherapy, most (80%) of which were men with a mean age of 59.5 years at diagnosis. SOMs mainly affected the floor of the mouth (60%) between the fourth and the sixth weeks of radiation therapy. All lesions were asymptomatic and spontaneously ruptured approximately 9 days after diagnosis. CONCLUSIONS: Although rare, SOMs may be regarded as an acute oral toxicity of head and neck radiotherapy. Key words:Superficial oral mucoceles; head and neck cancer; radiation toxicity, acute toxicity.

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