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Metabolic profiling of metformin treatment for low-level Pb-induced nephrotoxicity in rat urine

Chronic kidney disease is a worldwide problem, and Pb contamination is a potential risk factor. Since current biomarkers are not sensitive for the diagnosis of Pb-induced nephrotoxicity, novel biomarkers are needed. Metformin has both hypoglycaemic effects and reno-protection ability. However, its m...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Shen, Wang, Shwu-Huey, Chen, Shih-Ming, Lee, Jen-Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167321/
https://www.ncbi.nlm.nih.gov/pubmed/30275489
http://dx.doi.org/10.1038/s41598-018-32501-3

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