Calcium increases titin N2A binding to F-actin and regulated thin filaments

Mutations in titin are responsible for many cardiac and muscle diseases, yet the underlying mechanisms remain largely unexplained. Numerous studies have established roles for titin in muscle function, and Ca(2+)-dependent interactions between titin and actin have been suggested to play a role in mus...

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Detalles Bibliográficos
Autores principales: Dutta, Samrat, Tsiros, Christopher, Sundar, Sai Lavanyaa, Athar, Humra, Moore, Jeffrey, Nelson, Brent, Gage, Matthew J., Nishikawa, Kiisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167357/
https://www.ncbi.nlm.nih.gov/pubmed/30275509
http://dx.doi.org/10.1038/s41598-018-32952-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167357/
https://www.ncbi.nlm.nih.gov/pubmed/30275509
http://dx.doi.org/10.1038/s41598-018-32952-8

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