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Calcium increases titin N2A binding to F-actin and regulated thin filaments
Mutations in titin are responsible for many cardiac and muscle diseases, yet the underlying mechanisms remain largely unexplained. Numerous studies have established roles for titin in muscle function, and Ca(2+)-dependent interactions between titin and actin have been suggested to play a role in mus...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167357/ https://www.ncbi.nlm.nih.gov/pubmed/30275509 http://dx.doi.org/10.1038/s41598-018-32952-8 |