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Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer originating from mature B-cells. Prognosis is strongly associated with molecular subgroup, although the driver mutations that distinguish the two main subgroups remain poorly defined. Through an integrative analysis of whole genomes, exom...

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Detalles Bibliográficos
Autores principales: Arthur, Sarah E., Jiang, Aixiang, Grande, Bruno M., Alcaide, Miguel, Cojocaru, Razvan, Rushton, Christopher K., Mottok, Anja, Hilton, Laura K., Lat, Prince Kumar, Zhao, Eric Y., Culibrk, Luka, Ennishi, Daisuke, Jessa, Selin, Chong, Lauren, Thomas, Nicole, Pararajalingam, Prasath, Meissner, Barbara, Boyle, Merrill, Davidson, Jordan, Bushell, Kevin R., Lai, Daniel, Farinha, Pedro, Slack, Graham W., Morin, Gregg B., Shah, Sohrab, Sen, Dipankar, Jones, Steven J. M., Mungall, Andrew J., Gascoyne, Randy D., Audas, Timothy E., Unrau, Peter, Marra, Marco A., Connors, Joseph M., Steidl, Christian, Scott, David W., Morin, Ryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167379/
https://www.ncbi.nlm.nih.gov/pubmed/30275490
http://dx.doi.org/10.1038/s41467-018-06354-3