Regulatory control of DNA end resection by Sae2 phosphorylation

DNA end resection plays a critical function in DNA double-strand break repair pathway choice. Resected DNA ends are refractory to end-joining mechanisms and are instead channeled to homology-directed repair. Using biochemical, genetic, and imaging methods, we show that phosphorylation of Saccharomyc...

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Detalles Bibliográficos
Autores principales: Cannavo, Elda, Johnson, Dominic, Andres, Sara N., Kissling, Vera M., Reinert, Julia K., Garcia, Valerie, Erie, Dorothy A., Hess, Daniel, Thomä, Nicolas H., Enchev, Radoslav I., Peter, Matthias, Williams, R. Scott, Neale, Matt J., Cejka, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167383/
https://www.ncbi.nlm.nih.gov/pubmed/30275497
http://dx.doi.org/10.1038/s41467-018-06417-5

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