Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance

The century-old embryonal/gametogenesis hypothesis of tumors could link diverse tumors’ malignant features together likely representing the real “stemness” of tumors. However, the genetic evidence to validate abnormal gametogenesis in tumors remains lacking. Here we show that p53 deficiency elicits...

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Detalles Bibliográficos
Autores principales: Liu, Chunfang, Cai, Zhen, Jin, Guoxiang, Peng, Danni, Pan, Bo-Syong, Zhang, Xian, Han, Fei, Xu, Xiaohong, Lin, Hui-Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167385/
https://www.ncbi.nlm.nih.gov/pubmed/30302273
http://dx.doi.org/10.1038/s41421-018-0054-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167385/
https://www.ncbi.nlm.nih.gov/pubmed/30302273
http://dx.doi.org/10.1038/s41421-018-0054-x

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